Microbiology (BIO
108) – Chaps. 7&20: Microbial Control
Learning Objectives
1. Define the following: sterilization, disinfection, antisepsis, germicide, bacteriostasis,
asepsis.
2. Describe the pattern of microbial death caused by microbial control agents.
3. Describe the effects of microbial control agents on cellular structures.
4. Compare the effectiveness of moist heat and dry heat.
5. Describe the operation of an autoclave.
6. Explain how radiation kills cells.
7. List the factors related to effective disinfection.
8. Describe the contributions of Paul Ehrlich and Alexander Fleming in the field of
chemotherapy.
9. Identify the microbes that produce antibiotics and list five of these antibiotics..
10. Define the following: spectrum of activity, broad-spectrum antibiotic, superinfection.
11. Identify five modes of action of antimicrobial drugs.
12. Describe how each of the following inhibits protein synthesis: aminoglycosides, tetra-
cyclines, chloramphenicol, macrolides.
13. Describe two tests for microbial susceptibility to chemotherapeutic agents.
14. Describe two mechanisms of drug resistance.
15. Define all the boldface terms in chapters 7 and 20 and add these terms to your
vocabulary.