Regulation of Extracellular Flui

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Regulation of Extracellular Fluid Volume - The Renin - Angiotensin System

Macula densa of distal tubule

Text Box: Macula densa of distal tubule

Afferent arteriole cells

Text Box: Afferent arteriole cells

Juxtaglomerular apparatus

Hypovolemia and hypotension

Loss of water and sodium due to hemorrhage, vomiting, diarrhea, sweating

Text Box: Loss of water and sodium due to hemorrhage, vomiting, diarrhea, sweating

SNS stimulation
produces dilation of the afferent arteriole and constriction of the efferent arteriole

Text Box: SNS stimulation
produces dilation of the afferent arteriole and constriction of the efferent arteriole

CAC activation in the medulla oblongata

Text Box: CAC activation in the medulla oblongata

Stimulates baroreceptors of atrium and aorta

Text Box: Stimulates baroreceptors of atrium and aorta

Decreased venous return and filtration

Text Box: Decreased venous return and filtration

Increased fluid intake

Text Box: Increased fluid intake

Increased sodium and water retention

Text Box: Increased sodium and water retention

Release of the enzyme renin

Text Box: Release of the enzyme renin

Increased filtration

Text Box: Increased filtration

Increased extracellular fluid volume and blood pressure

Text Box: Increased extracellular fluid volume and blood pressure

Shunts blood to core of body

Text Box: Shunts blood to core of body

Stimulates adrenal cortex to release aldosterone

Text Box: Stimulates adrenal cortex to release aldosterone

Stimulates Hypothalamus producing thirst

Text Box: Stimulates Hypothalamus producing thirst

Vasoconstriction of peripheral blood vessels

Text Box: Vasoconstriction of peripheral blood vessels

Angiotensin II

Angiotensin I

Angiotensinogen