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Black Death
 http://www.wikipedia.org/wiki/Black_Death
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The Black Death (also Bubonic Plague or The Plague, and latterly Black Plague though not called this in earlier times) was a devastating epidemic in Europe in the 14th century which is estimated to have killed about a third of the population. Most scientists believe that the Black Death was an outbreak of bubonic plague, a dreaded disease that has spread in pandemic form several times through history. The plague is caused by the bacterium Yersinia pestis which is spread by fleas with the help of animals like the black rat (Rattus rattus). Sometime, the term "Black Death" is used for all outbreaks of plague.

It is not entirely clear where the major epidemic of the 14th century started, but it was probably somewhere around the northern parts of India. It then spread west to the Middle East. The plague was imported to Europe by the way of the Crimea, where the Genoese colony Kaffa (Feodosiya) was besieged by the Mongols. Myth (or history?) says that the Mongols catapulted infected cadavers into the city. The refugees from Kaffa then took the plague along to Messina, Genoa and Venice, around the turn of 1347/1348. Some ships didn't have anyone alive when they reached their port. From Italy the disease spread clockwise around Europe, hitting France, Spain, Britain, Germany, Scandinavia and finally north-western Russia around 1351.

The information about the death toll varies widely from source to source, but it is estimated that about a third of the population of Europe died from the outbreak in the mid-1300s. Approximately 25 million deaths occurred in Europe alone with many others occurring in Africa and Asia. Some villages were deserted with the few survivors fleeing and spreading the disease further. The great population loss brought economic changes based on increased social mobility as depopulation elsewhere eroded peasant obligations (already weakened) to remain on their traditional holdings.